SAMJ: South African Medical Journal
On-line version ISSN 2078-5135
MULLER, Elmi; BARDAY, Zunaid; MENDELSON, Marc and KAHN, Delawir. Renal transplantation between HIV-positive donors and recipients justified. SAMJ, S. Afr. med. j. [online]. 2012, vol.102, n.6, pp. 497-498. ISSN 2078-5135.
HIV infection was previously an absolute contraindication to renal transplantation. However, with the advent of highly active antiretroviral therapy (HAART), renal transplantation using HIV-negative donor kidneys has successfully been employed for HIV-infected patients with end-stage renal failure. In resource-limited countries, places on dialysis programmes are severely restricted; HIV-infected patients, like many others with co-morbidity, are often denied treatment. Kidneys (and other organs) from HIV-infected deceased donors are discarded. The transplantation of HIV-positive donor kidneys to HIV-infected recipients is now a viable alternative to chronic dialysis or transplantation of HIV-negative donor kidneys. This significantly increases the pool of donor kidneys to the advantage of HIV-positive and -negative patients. Arguments are presented that led to our initiation of renal transplantation from HIV-positive deceased donors to HIV-positive recipients at Groote Schuur Hospital, Cape Town.