SciELO - Scientific Electronic Library Online

 
vol.56 número3Laparoscopic splenectomy: Consensus and debatable pointsAnalysis of epidemiology, lesions, treatment and outcome of 354 consecutive cases of blunt and penetrating trauma to the chest in an African setting índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Em processo de indexaçãoSimilares em Google

Compartilhar


South African Journal of Surgery

versão On-line ISSN 2078-5151
versão impressa ISSN 0038-2361

Resumo

MALITH, V; BOMBIL, I; HARRAN, N  e  LUVHENGO, TE. Demographic and histological subtypes of Hurthle cell tumours of the thyroid in a South African setting. S. Afr. j. surg. [online]. 2018, vol.56, n.3, pp.20-23. ISSN 2078-5151.  http://dx.doi.org/10.17159/2078-5151/2018/v56n3a2557.

BACKGROUND: Report of Hurthle cells following fine needle aspiration cytology from a thyroid nodule raises possibility of Hurthle cell carcinoma (HCC), which is a distinct entity and accounts for 3-10% of thyroid malignancies. AIM: To determine if there are demographic and histopathological features which may be used to differentiate HCC from Hurthle cell adenoma (HCA) METHODS: Histopathology records of patients who had thyroidectomy from January 2001 to October 2015 were reviewed. Data retrieved included indications for thyroidectomy, patients' demographics, histology and preoperative FNAC results. RESULTS: At total of 2641 records were reviewed of which 25.6% (676/2641) were for neoplasms. 15.8% (107/676) of the neoplasms were Hurthle cell neoplasms (HCNs) and 25.2% (27/107) of HCNs were HCCs. 77.2% (71/92) of HCAs and 77.8% (21/27) of HCCs were from female patients. Preoperative FNAC results were available for 54.2% (58/107) and were suspicious of HCN in 12.1% (7/58). Average tumour size for HCCs and HCAs was 4.9 +/- 2.7 cm and 3.5 +/- 2.0 cm, respectively. The difference was statistically significant with a p-value of 0.016. The risk of malignancy increased from 11.1% in HCNs less than 1 cm to 53.8% for tumours which were greater than 4 cm in diameter. CONCLUSION: HCNs are more common in females. The likelihood of HCC rises as the size of the HCN increases. Malignancy rate exceeds 50% for HCNs which are greater than 4 cm in diameter

Palavras-chave : Hurthle cell neoplasm; Hurthle cell carcinoma; FNA; tumour size.

        · texto em Inglês     · Inglês ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons