Abstract

LOOTS, E. The role of surgery in an imatinib-resistant GIST liver secondary. S. Afr. j. surg. [online]. 2015, vol.53, n.2, pp.70-71. ISSN 2078-5151.  http://dx.doi.org/10.7196/SAJSNEW.7861.

This is a case report describing the management of an imatinib-resistant liver secondary as a result of an exon 13 mutation. The gastric primary was completely excised 3 years prior and proven to contain an exon 11 mutation. Resective liver surgery was undertaken after the patient developed imatinib resistance and he has been disease-free for 19 months. The application of surgery in the context of other treatment options is discussed.

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