South African Journal of Science
versão On-line ISSN 1996-7489
versão impressa ISSN 0038-2353
OUIFKI, R.; WELTE, A. e PRETORIUS, C.. A model of HIV infection with two viral strains and cytotoxic T-lymphocyte response under structured treatment interruptions. S. Afr. j. sci. [online]. 2008, vol.104, n.5-6, pp.216-220. ISSN 1996-7489.
We develop a model of HIV infection with two viral strains, a cytotoxic T-lymphocyte (CTL) response and structured treatment interruptions. We derive new analytical relations characterizing the dynamics between drug-sensitive and drug-resistant variants of the virus, and the strength of the CTL response.