Abstract

THEKISO, MD; YENGOPAL, V  and  RUDOLPH, MJ. The relationship between oral candidiasis and micronutrient deficiency amongst adult tuberculosis patients in Alexandra, Johannesburg. S. Afr. dent. j. [online]. 2018, vol.73, n.8, pp.489-498. ISSN 0375-1562.  http://dx.doi.org/10.17159/2519-0105/2018/v73no8a2.

INTRODUCTION: Tuberculosis (TB), a major public health problem worldwide, is associated with micronutrient deficiency and wasting, and co-infections could worsen the condition AIM: To investigate the relationship between micronutrient deficiency and oral candidiasis in adult TB patients METHODS: A cross-sectional study among 88 TB adult patients in Alexandra, Johannesburg. Patients underwent a complete oral examination to establish the prevalence of candidiasis and blood was collected for the assessment of micronu-trient levels RESULTS: The mean age of participants was 36.66 years of age, the majority being female (60.23%) and HIV positive (69.30%). The prevalence of oral candidiasis was 39.77% with pseudomembranous being most common (48.00%). In those with micronutrient deficiencies, oral candidiasis was prevalent in 40% patients with Zinc deficiency, 25.00% with Vitamin A deficiency, 32.00% with Albumin deficiency, 33.00% with Selenium deficiency, 31.00% with Iron deficiency and in 36.00% with Vitamin D deficiency CONCLUSION: There was a significant association between the presence of oral candidiasis in TB/HIV co-infected patients and Zinc, Vitamin A and Vitamin D- deficiencies, but not in the TB only group

Keywords : Tuberculosis; Human Immunodeficiency Virus; Oral Candidiasis; Zinc; Iron; Albumin; Selenium; Vitamin A and Vitamin D micronutrient deficiency.

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