Resumen

ZWANE, NB; MOHANGI, GU  y  SHANGASE, SL. Head and neck cancers among HIV-positive patients: A five year retrospective study from a Johannesburg hospital, South Africa. S. Afr. dent. j. [online]. 2018, vol.73, n.3, pp.121-126. ISSN 0375-1562.

INTRODUCTION: Cancer is a significant cause of morbidity and mortality among HIV infected individuals, but information is lacking in South Africa regarding Head and Neck AIDS-defining cancers (ADCs). AIM To profile head and neck cancers (HNC) in HIV-positive patients in the Department of Oral Pathology, Wits Oral Health Centre over a five year period. Methods and data analysis: A records-based retrospective descriptive study with an analytic component. Archived records (2009 to 2013) in the Department of Oral Pathology were reviewed. HIV serology results, CD4+T-cell counts and the viral load were verified from National Health Laboratory Service archived records. IBM SPSS 23.0 was used for data analysis. RESULTS 1605 cases of HNC were recorded, with 389 (24.2%) confirmed HIV-positive ( mean age of 38 ± 11.0 years), of whom 52.3% were females . The likelihood of patients with HIV infection to be diagnosed with Kaposi Sarcoma (KS)and Non Hodgkin's Lymphoma(NHL) was significantly greater at 35.7% and 34.2% respectively with a p value < 0.05, compared with any other cancer type. CONCLUSION: KS and NHL, both ADCs, were the two most common HNCs diagnosed among HIV-positive patients. Third was Oral squamous cell carcinoma (OSCC), a Non Aids Defining Cancer (NADC).

Palabras clave : Head and neck cancer; AIDS-defining cancer; Non-AIDS-defining cancer; Kaposi sarcoma; Non-Hodgkin's lymphoma; Oral squamous cell carcinoma.

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