Abstract

MORTAZAVI, H; EBRAHIMI, S; BAHARVAND, M  and  SABOUR, S. Salivary Creatine Kinase MB in myocardial infarction. S. Afr. dent. j. [online]. 2016, vol.71, n.3, pp.112-115. ISSN 0375-1562.

INTRODUCTION: Most biomarkers in the blood and urine can also be detected in salivary samples. AIMS AND OBJECTIVES: To determine the relationship. between serum and salivary levels of Creatine Kinase MB in patients with acute myocardial infarction. DESIGN: In a case-control study, forty-one patients diagnosed with myocardial infarction and forty- two age and sex- matched controls were enrolled. METHODS: Saliva sampling by the spitting method was performed 12 to 24 hours after myocardial infarction, and in controls, between 9am and 12 noon. Salivary Creatine Kinase MB levels were measured by the photometric method. Mann Whitney U test and Spearman coefficient were used to analyze the data. RESULTS: There was no significant difference between patients with myocardial infarction and the controls in terms of the salivary levels of creatine kinase MB (case: 24 U/l vs. : 19.5 U/l, p=0.30). Patients showed no significant difference in median levels of salivary creatine kinase MB in terms of sex (p=0.69) and previous history of myocardial infarction (p=0.31). In all patients there was a weak positive relationship between serum and salivary levels of creatine kinase MB (rs=0.14, p= 0.39). CONCLUSIONS: Salivary creatine kinase MB level cannot be an indicator for diagnosis of myocardial infarction.

Keywords : Creatine Kinase MB; saliva; myocardial infarction.

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