RESEARCH ARTICLE

 

Interaction of hydroxyproline with bivalent metal ions in chemical and biological systems

 

 

Brij B. Tewari^*

Department of Chemistry, Faculty of Natural Sciences, University of Guyana, P. O. Box 101110, Georgetown, Guyana

 

 

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ABSTRACT

A recent technique involving the use of paper electrophoresis is described for the study of equilibria in binary complex systems in solution. The stability constants of the ML and ML₂ complex species of some metal ions, namely beryllium(II) and cobalt(II), with hydroxyproline were determined in 0.1 mol L^-1 perchloric acid and a temperature of 35 °C. The logarithm stability constants of the ML and ML₂ complexes of hydroxyproline were found to be 7.39 ± 0.07 and 5.90 ± 0.03, and 4.73 ± 0.08 and 3.71 ± 0.11 for the beryllium(II) and cobalt(II) complexes, respectively.

Keywords: Hydroxyproline, paper electrophoresis, stability constants

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Received 18 June 2009
Revised 18 July 2010
Accepted 17 October 2010

 

 

* E-mail: brijtew@yahoo.com