Scielo RSS <![CDATA[South African Dental Journal ]]> http://www.scielo.org.za/rss.php?pid=0011-851620160001&lang=pt vol. 71 num. 1 lang. pt <![CDATA[SciELO Logo]]> http://www.scielo.org.za/img/en/fbpelogp.gif http://www.scielo.org.za <![CDATA[<b>Why do some birds hop and others walk?</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100001&lng=pt&nrm=iso&tlng=pt <![CDATA[<b>Communique, Communique</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100002&lng=pt&nrm=iso&tlng=pt <![CDATA[<b>Dr Harold Levenstein</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100003&lng=pt&nrm=iso&tlng=pt <![CDATA[<b>Maryna Ras Ferreira</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100004&lng=pt&nrm=iso&tlng=pt <![CDATA[<b>Aubrey Sheiham</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100005&lng=pt&nrm=iso&tlng=pt <![CDATA[<b>Antifungal susceptibility of <i>Candida albicans </i>isolated from the oral cavities of patients with HIV infection and cancer</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100006&lng=pt&nrm=iso&tlng=pt This study investigated the antifungal susceptibility of Candida albicans isolated from the oral cavities of 205 HIV positive patients, 49 cancer patients and 20 normal healthy individuals. C. albicans were isolated and the antifungal susceptibility was determined. The results were analysed using the clinical break points and epidemiological cut off values. Prevalence of C. albicans carriage in HIV, in cancer patients, and in healthy individuals was 73%, 45% and 43% respectively. Resistance of the fungus to anidulafungin (0.49%), caspofungin (0.97%), posaconazole (3.4%), voriconazole (0.97%), itraconazole (0.97%), fluconazole (1.94%), amphotericin B (0%) was found to be low. For posaconazole the number of resistant strains and the non-wild type (3.4%) were the same. However for the rest of the antifungal drugs, the number of non-wild type was found to be higher than the resistance determined by clinical break points. Multi-azole resistance was also noted in some patients. In conclusion, there is a low rate of antifungal drug resistance among C. albicans isolated from the oral cavities of immunocompromised patients in Johannesburg, South Africa. However, the high number of non-wild type strains suggests that there is a need for an ongoing surveillance. <![CDATA[<b>The perceptions of South African dentists on strategic management to ensure a viable dental practice</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100007&lng=pt&nrm=iso&tlng=pt OBJECTIVES: How do dentists perceive the influence of the external environment on, and what is their confidence in, planning the strategic management of their practices? METHODS: A cross-sectional survey using an anonymous online questionnaire was conducted among private dental practitioners, members of the South African Dental Association. Stata release 11 was used for descriptive data analysis, including determination of frequencies RESULTS: The majority of the respondents work 40-44 hours, see more than 70 patients per week and are fairly satisfied with those numbers. Only 27.56% of practices confirmed written vision/mission statements. One third (33.78%) were only moderately confident they could plan and execute strategies to ensure a viable practice. Almost a tenth (8.11%) does not feel confident at all. Medical schemes, disposable income of patients and dentist-patient communication were the most significant challenges. Clinical practice was more satisfying than the business side CONCLUSION: Dental practices are increasingly complex, with a myriad of challenges. Ideally the dentist as owner/ manager/leader, should be able to strategise management of the external and internal environments to achieve the vision, mission and objectives of the practice. Dental schools, in collaboration with SADA, should work towards equipping dentists with the necessary management and strategic thinking skills to ensure success <![CDATA[<b>The association between area level socio-economic position and oral health-related quality of life in the South African adult population</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100008&lng=pt&nrm=iso&tlng=pt OBJECTIVE: To investigate the association between area-level socio-economic position (SEP) and oral health-related quality of life (OHRQoL METHODS: Data collected from a nationally representative sample of the South African population >16 years old (n=3,003) included demographics, individual-level SEP measures and self-reported oral health status. OHRQoL was measured using the Oral Health Impact Profile-14 (OHIP-14). The General Household Survey (n=25,653 households) and Quarterly Labour Force Surveys (n~30,000 households/ quarter) were used to determine area-level SEP. Data analysis included a random-effect negative binomial regression model and Blinder-Oaxaca decomposition analysis RESULTS: Area-level deprivation was associated with more negative oral impacts, independent of an individual's SEP. Other significant predictors of oral impacts included having experienced oral pain (β=1.15) and reporting previous dental visits (β=0.69). Area differences in dental attendance contributed the most (37.5%) to the observed gap in OHRQoL, explained by differences in area-level SEP, whereas individual-level SEP contributed the least (18.8%). In the more affluent areas, satisfaction with life in general and individuals' SEP were significantly positively associated with OHRQoL CONCLUSION: To reduce inequalities in OHRQoL, proportionate development of socio-economic conditions should be prioritised, particularly there appears to be a need for greater access to oral health services by disadvantaged people in affluent areas <![CDATA[<b>The emerging role of epigenetics in the pathogenesis of periodontitis - A review</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100009&lng=pt&nrm=iso&tlng=pt Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. It is a complex disease with multifactorial etiology. Numerous studies have examined the role of the genetic factors in the etiology of periodontitis. Epigenetics is the study of the mitotically and meiotically heritable changes in the gene function that cannot be explained by changes in the DNA sequence. Studies have demonstrated that epigenetic alterations contribute to a number of diseases like cancer, metabolic and autoimmune disorders. An understanding of the epigenetic mechanisms helps to develop novel therapeutic aids which target the specific epigenetic sites. This article attempts to shed light on the role of epigenetic alterations in the pathogenesis of periodontitis. The role of the bacteria-induced epigenetic alterations in the host cell, the alterations in the cytokine profile and the role of the environmental factors like smoking on the epigenome are reviewed. Technological advances have enabled us to analyse and quantify the epigenetic changes on a large scale. Drugs which specifically target the epigenetic mechanisms may be used as valuable adjuncts to conventional periodontal therapy leading the way to personalized and preventive regimes. <![CDATA[<b>Continuous education in sedation: Laryngospasm and management of the airway</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100010&lng=pt&nrm=iso&tlng=pt Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. It is a complex disease with multifactorial etiology. Numerous studies have examined the role of the genetic factors in the etiology of periodontitis. Epigenetics is the study of the mitotically and meiotically heritable changes in the gene function that cannot be explained by changes in the DNA sequence. Studies have demonstrated that epigenetic alterations contribute to a number of diseases like cancer, metabolic and autoimmune disorders. An understanding of the epigenetic mechanisms helps to develop novel therapeutic aids which target the specific epigenetic sites. This article attempts to shed light on the role of epigenetic alterations in the pathogenesis of periodontitis. The role of the bacteria-induced epigenetic alterations in the host cell, the alterations in the cytokine profile and the role of the environmental factors like smoking on the epigenome are reviewed. Technological advances have enabled us to analyse and quantify the epigenetic changes on a large scale. Drugs which specifically target the epigenetic mechanisms may be used as valuable adjuncts to conventional periodontal therapy leading the way to personalized and preventive regimes. <![CDATA[<b>Maxillofacial radiology case 137</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100011&lng=pt&nrm=iso&tlng=pt Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. It is a complex disease with multifactorial etiology. Numerous studies have examined the role of the genetic factors in the etiology of periodontitis. Epigenetics is the study of the mitotically and meiotically heritable changes in the gene function that cannot be explained by changes in the DNA sequence. Studies have demonstrated that epigenetic alterations contribute to a number of diseases like cancer, metabolic and autoimmune disorders. An understanding of the epigenetic mechanisms helps to develop novel therapeutic aids which target the specific epigenetic sites. This article attempts to shed light on the role of epigenetic alterations in the pathogenesis of periodontitis. The role of the bacteria-induced epigenetic alterations in the host cell, the alterations in the cytokine profile and the role of the environmental factors like smoking on the epigenome are reviewed. Technological advances have enabled us to analyse and quantify the epigenetic changes on a large scale. Drugs which specifically target the epigenetic mechanisms may be used as valuable adjuncts to conventional periodontal therapy leading the way to personalized and preventive regimes. <![CDATA[<b>Advertising your additional qualifications</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100012&lng=pt&nrm=iso&tlng=pt Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. It is a complex disease with multifactorial etiology. Numerous studies have examined the role of the genetic factors in the etiology of periodontitis. Epigenetics is the study of the mitotically and meiotically heritable changes in the gene function that cannot be explained by changes in the DNA sequence. Studies have demonstrated that epigenetic alterations contribute to a number of diseases like cancer, metabolic and autoimmune disorders. An understanding of the epigenetic mechanisms helps to develop novel therapeutic aids which target the specific epigenetic sites. This article attempts to shed light on the role of epigenetic alterations in the pathogenesis of periodontitis. The role of the bacteria-induced epigenetic alterations in the host cell, the alterations in the cytokine profile and the role of the environmental factors like smoking on the epigenome are reviewed. Technological advances have enabled us to analyse and quantify the epigenetic changes on a large scale. Drugs which specifically target the epigenetic mechanisms may be used as valuable adjuncts to conventional periodontal therapy leading the way to personalized and preventive regimes. <![CDATA[<b>What's new for the clinician? Summaries of and excerpts from recently published papers</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100013&lng=pt&nrm=iso&tlng=pt Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. It is a complex disease with multifactorial etiology. Numerous studies have examined the role of the genetic factors in the etiology of periodontitis. Epigenetics is the study of the mitotically and meiotically heritable changes in the gene function that cannot be explained by changes in the DNA sequence. Studies have demonstrated that epigenetic alterations contribute to a number of diseases like cancer, metabolic and autoimmune disorders. An understanding of the epigenetic mechanisms helps to develop novel therapeutic aids which target the specific epigenetic sites. This article attempts to shed light on the role of epigenetic alterations in the pathogenesis of periodontitis. The role of the bacteria-induced epigenetic alterations in the host cell, the alterations in the cytokine profile and the role of the environmental factors like smoking on the epigenome are reviewed. Technological advances have enabled us to analyse and quantify the epigenetic changes on a large scale. Drugs which specifically target the epigenetic mechanisms may be used as valuable adjuncts to conventional periodontal therapy leading the way to personalized and preventive regimes. <![CDATA[<b>Pain</b><b> after single-visit root canal treatment with two single-file systems: A prospective RCT</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100014&lng=pt&nrm=iso&tlng=pt Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. It is a complex disease with multifactorial etiology. Numerous studies have examined the role of the genetic factors in the etiology of periodontitis. Epigenetics is the study of the mitotically and meiotically heritable changes in the gene function that cannot be explained by changes in the DNA sequence. Studies have demonstrated that epigenetic alterations contribute to a number of diseases like cancer, metabolic and autoimmune disorders. An understanding of the epigenetic mechanisms helps to develop novel therapeutic aids which target the specific epigenetic sites. This article attempts to shed light on the role of epigenetic alterations in the pathogenesis of periodontitis. The role of the bacteria-induced epigenetic alterations in the host cell, the alterations in the cytokine profile and the role of the environmental factors like smoking on the epigenome are reviewed. Technological advances have enabled us to analyse and quantify the epigenetic changes on a large scale. Drugs which specifically target the epigenetic mechanisms may be used as valuable adjuncts to conventional periodontal therapy leading the way to personalized and preventive regimes. <![CDATA[<b>ERRATUM</b>]]> http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0011-85162016000100015&lng=pt&nrm=iso&tlng=pt Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. It is a complex disease with multifactorial etiology. Numerous studies have examined the role of the genetic factors in the etiology of periodontitis. Epigenetics is the study of the mitotically and meiotically heritable changes in the gene function that cannot be explained by changes in the DNA sequence. Studies have demonstrated that epigenetic alterations contribute to a number of diseases like cancer, metabolic and autoimmune disorders. An understanding of the epigenetic mechanisms helps to develop novel therapeutic aids which target the specific epigenetic sites. This article attempts to shed light on the role of epigenetic alterations in the pathogenesis of periodontitis. The role of the bacteria-induced epigenetic alterations in the host cell, the alterations in the cytokine profile and the role of the environmental factors like smoking on the epigenome are reviewed. Technological advances have enabled us to analyse and quantify the epigenetic changes on a large scale. Drugs which specifically target the epigenetic mechanisms may be used as valuable adjuncts to conventional periodontal therapy leading the way to personalized and preventive regimes.